Published February 1967
| Published
Journal Article
Open
The Process of Infection with Bacteriophage øX174 XIII. Evidence for an Essential Bacterial "Site"
- Creators
- Yarus, Michael J.
- Sinsheimer, Robert L.
Abstract
The burst of a starved bacterium infected with several øX174 bacteriophage was usually found to contain genetic traits of only one of the possible parents; less often, two phage multiplied in the same host cell. Unstarved cells, in contrast, supported the growth of at least four parental phage types. The unproductive phage seemed to be able to undergo the intracellular transition from parental single-stranded deoxyribonucleic acid to the double-stranded "replicative form" (RF). These results are taken to mean that some bacterial factor required for a step between RF synthesis and maturation of progeny is limited in starved cells.
Additional Information
© 1967 American Society for Microbiology. Received for publication 31 October 1966. This investigation was supported by Public Health Service grants RG6965 and GM13554. C.A. Hutchison III supplied several of the φX mutants used in this work, and we thank him both for these and for many helpful discussions. David Denhardt collaborated in the experiment represented in Fig. 1. From a thesis submitted by M. Yarus to the California Institute of Technology in partial fulfillment of the requirements for the Ph.D. degree. http://resolver.caltech.edu/CaltechETD:etd-09232002-152158Attached Files
Published - YARjvir67.pdf
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YARjvir67.pdf
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Additional details
- PMCID
- PMC375514
- Eprint ID
- 9838
- Resolver ID
- CaltechAUTHORS:YARjvir67
- RG6965
- NIH
- GM13554
- NIH
- Created
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2008-03-20Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field