Published August 1978
| Published
Journal Article
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A Drosophila Mutant with a Temperature-Sensitive Block in Nerve Conduction
Chicago
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Abstract
A mutant, napts (no action potential, temperature-sensitive), is described in which axonal conduction fails at high temperature. Synaptic transmission at the larval neuromuscular junction is unimpaired. Larvae and adults are rapidly paralyzed at restrictive temperatures; they recover rapidly when the temperature is decreased. The mutant gene is recessive and is located on the second chromosome at map position 56.
Additional Information
© 1978 National Academy of Sciences. Contributed by Seymour Benzer, May 26, 1978. We thank our colleagues for constant comment, particularly Lawrence Kauvar and Duncan Byers. This work was supported by National Science Foundation Grant PCM73-01972. C-F.W., B.G., Y-N.J., and L.Y.J. held fellowships from, respectively, the Spencer, Jane Coffin Childs, and Muscular Dystrophy Foundations and the National Institutes of Health.Attached Files
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Additional details
- PMCID
- PMC392928
- Eprint ID
- 4747
- Resolver ID
- CaltechAUTHORS:WUCpnas78
- NSF
- PCM73-01972
- Spencer Foundation
- Jane Coffin Childs Foundation
- Muscular Dystrophy Foundation
- NIH
- Created
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2006-09-05Created from EPrint's datestamp field
- Updated
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2019-10-02Created from EPrint's last_modified field