α-Aminoadipic acid as a precursor to lysine in Neurospora
- Creators
- Windsor, Emanuel
Abstract
In a recent investigation reported by Mitchell and Houlahan (1) it was shown that a mutant strain of Neurospora crassa, strain 33933, was able to utilize α-aminoadipic acid in place of lysine. Although these authors interpreted their results as showing that oc-aminoadipic acid was a precursor in the biosynthesis of lysine by Neurospora, other pathways are conceivable. During the isolation of α-aminoadipic acid from a natural protein radioactive α-aminoadipic acid was added as a marker for chromatographic analysis (2). In order to identify the isolated amino acid an aliquot was provided as a growth substance for the Neurospora mutant 33933. Thus the opportunity was available to follow the radioactivity and determine whether or not α-aminoadipic acid was a precursor to lysine.
Additional Information
Copyright © 1951 by the American Society for Biochemistry and Molecular Biology. (Received for publication, May 22, 1951) Part of this work was taken from a thesis in partial fulfilment of the requirements for the degree of Doctor of Philosophy.Files
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Additional details
- Eprint ID
- 6204
- Resolver ID
- CaltechAUTHORS:WINjbc51a
- Created
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2006-11-28Created from EPrint's datestamp field
- Updated
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2019-10-02Created from EPrint's last_modified field