Published July 1, 1953
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Journal Article
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Induction of Mutations in a Bacterial Virus
- Creators
- Weigle, J. J.
Chicago
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Abstract
In the course of experiments designed for other purposes a paradoxical observation was made: phage λ, inactivated by UV irradiation, when adsorbed onto sensitive bacteria was reactivated when a further dose of UV was given to the phage-bacterium complexes. Among the reactivated phages a fairly large proportion were mutants. A description of these findings and a discussion of their implications will be found below.
Additional Information
Copyright © 1953 by the National Academy of Sciences Communicated by M. Delbrück, May 12, 1953 The author gratefully acknowledges the constant help and advice he received in the course of this investigation from Dr. M. Delbrück, Dr. R. Dulbecco, and Dr. M. Vogt. He is also indebted to Dr. R. Appleyard, Dr. M. Lieb, and Mr. D. Kaiser for the bacterial strains used and for communications of unpublished results. This investigation was supported by a grant from the National Foundation for Infantile Paralysis.Files
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Additional details
- Eprint ID
- 6236
- Resolver ID
- CaltechAUTHORS:WEIpnas53
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