Published March 15, 1990
| Published
Journal Article
Open
Characterization of the transverse relaxation rates in lipid bilayers
- Creators
- Watnick, Paula I.
- Dea, Phoebe
-
Chan, Sunney I.
Chicago
An error occurred while generating the citation.
Abstract
The 2H NMR transverse relaxation rates of a deuterated phospholipid bilayer reflect slow motions in the bilayer membrane. A study of dimyristoyl lecithin specifically deuterated at several positions of the hydrocarbon chains indicates that these motions are cooperative and are confined to the hydrocarbon chains of the lipid bilayer. However, lipid head group interactions do play an important role in modulating the properties of the cooperative fluctuations of the hydrocarbon chains (director fluctuations), as evidenced by the effects of various lipid additives on the 2H NMR transverse relaxation rates of the dimyristoyl lecithin bilayer.
Additional Information
© 1990 by the National Academy of Sciences. Communicated by Harden M. McConnell, December 26, 1989. We are indebted to M. Dea, H. Eckert, T. Handel, A. Nayeem, and J. Yesinowski for helpful discussions and assistance. This work was supported by Grants GM-22432 (to S.I.C.), GM-36132 (to P.D.), and RR-08101 (to P.D.) from the National Institutes of General Medical Sciences, U.S. Public Health Service; and Petroleum Research Fund Grant 20212-B4 (to P.D.) administered by the American Chemical Society. P.I.W. was a recipient of National Research Service Award T32 GM07616 from the National Institutes of General Medical Sciences. Access to the Southern California Regional NMR Facility at Caltech, supported by Grant CHE84-40137 from the National Science Foundation, for the NMR experiments is gratefully acknowledged. This is contribution 7974 from the Division of Chemistry and Chemical Engineering. The publication costs of this article were defrayed in part by page charge payment. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. §1734 solely to indicate this fact.Attached Files
Published - WATpnas90.pdf
Files
WATpnas90.pdf
Files
(893.3 kB)
| Name | Size | Download all |
|---|---|---|
|
md5:fe6879329bcf69919a14a8ef9864e38e
|
893.3 kB | Preview Download |
Additional details
- PMCID
- PMC53630
- Eprint ID
- 1108
- Resolver ID
- CaltechAUTHORS:WATpnas90
- NIH
- GM-22432
- NIH
- GM-36132
- NIH
- RR-08101
- National Institute of General Medical Sciences
- American Chemical Society Petroleum Research Fund
- 20212-B4
- NIH Predoctoral Fellowship
- T32 GM07616
- NSF
- CHE84-40137
- Created
-
2005-12-20Created from EPrint's datestamp field
- Updated
-
2019-10-02Created from EPrint's last_modified field
- Other Numbering System Name
- Caltech Division of Chemistry and Chemical Engineering
- Other Numbering System Identifier
- 7974