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Published September 1976 | Published
Journal Article Open

Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster

Abstract

A new temperature-sensitive paralytic mutant of Drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi. All three have different properties with respect to kinetics of paralysis at high temperature and recovery from paralysis; com is hypersensitive to paralysis by cooling. Neurophysiological experiments indicate different mechanisms for paralysis in each of the mutants.

Additional Information

© 1976 by the National Academy of Sciences. Contributed by Seymour Benzer, July 6, 1976. We acknowledge the excellent technical assistance of Paul Christensen. This research was supported by Grant no. PCM 73-01972 from the National Science Foundation to S.B. and by a Gosney Research Fellowship to O.S.

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