Published February 2005
| Published
Book Section - Chapter
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On-chip temperature gradient liquid chromatography
- Creators
- Shih, C. Y.
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Chen, Y.
- Xie, J.
- He, Q.
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Tai, Y. C.
Chicago
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Abstract
We report here the first MEMS temperature-programmable high pressure parylene column with integrated thermal isolation and electrochemical sensor for on-chip temperature gradient liquid chromatography. Two sets of devices for different high performance liquid chromatography (HPLC) criteria were fabricated. The separation and detection of derivatized amino acids sample was successfully demonstrated. Compared with other temperature gradient HPLC systems which use "macro oven" to generate temporal temperature gradient in the column, our device's thermal performance is greatly improved by orders of magnitude without the sacrifice of chromatography quality.
Additional Information
© Copyright 2005 IEEE. Reprinted with permission. Publication Date: 30 Jan.-3 Feb. 2005. This work is supported by the NSF Center for Neuromorphic Systems Engineering (CNSE) at Caltech.Attached Files
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Additional details
- Eprint ID
- 12625
- Resolver ID
- CaltechAUTHORS:SHImems05
- Center for Neuromorphic Systems Engineering, Caltech
- NSF
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2008-12-16Created from EPrint's datestamp field
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2021-11-08Created from EPrint's last_modified field