Published July 1970
| Published
Journal Article
Open
Replicative form II DNA of phiX174; Resistance to exonucleolytic cleavage by E. coli DNA polymerase
- Creators
- Razin, Aharon
- Sinsheimer, Robert L.
Abstract
The progeny replicative form II DNA isolated from E. coli cells infected with phiX174 is resistant to the exonucleolytic activity associated with E. coli DNA polymerase. A limited endonucleolytic cleavage with micrococcal endonuclease renders the replicative form II molecule susceptible to the exonucleolytic activity associated with the E. coli DNA polymerase. These experiments suggest that the resistance of the replicative form II DNA to the exonucleolytic activity is a result of the structure of these molecules at their 5'-terminus.
Additional Information
© 1970 by the National Academy of Sciences. Communicated April 15, 1970. This research was supported in part by a grant from the U.S. Public Health Service GM-13534 and a postdoctoral research fellowship 1 F05, TW-1348 to A.R.Attached Files
Published - RAZpnas70.pdf
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Additional details
- PMCID
- PMC283099
- Eprint ID
- 9301
- Resolver ID
- CaltechAUTHORS:RAZpnas70
- GM13534
- U.S. Public Health Service (USPHS)
- 1 F05, TW-1348
- NIH Postdoctoral Fellowship
- Created
-
2007-12-12Created from EPrint's datestamp field
- Updated
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2019-10-02Created from EPrint's last_modified field