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Published April 25, 2000 | Published
Journal Article Open

Regulatory evolution and the origin of the bilaterians

Abstract

The adult body plan of bilaterians is achieved by imposing regional specifications on pluripotential cells. The establishment of spatial domains is governed in part by regulating expression of transcription factors. The key to understanding bilaterian evolution is contingent on our understanding of how the regulation of these transcription factors influenced bilaterian stem-group evolution.

Additional Information

© 2000 by the National Academy of Sciences. We thank Profs. Ellen Rothenberg (California Institute of Technology) and William McGinnis (University of California at San Diego) for helpful reviews. This work was supported by the Fundamental Biology Research Program of the Life Sciences Division of the National Aeronautic and Space Administration/Ames, Grant no. NAG 2–1368.

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