Published March 1968
| Published
Journal Article
Open
The process of infection with bacteriophage phiX174, XXII. Synthesis of progeny single-stranded DNA
Chicago
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Abstract
In a previous article,(1) it was demonstrated that of the labeled thymidine incorporated into the replicative form (RF) of phiX-DNA during the period of RF replication (3-12 or 15 min after infection), approximately half was transferred to virus during the subsequent period of single-strand DNA synthesis, while half remained in RF molecules. In this paper experiments are presented which permit a definition of the label remaining in the RF and which clarify the role of the RF in the synthesis of the progeny single-stranded DNA.
Additional Information
© 1968 by the National Academy of Sciences. Communicated December 20, 1967. We are indebted to Dr. M. Goulian for a generous gift of purified exonuclease III and to Mrs. Louise Wilson for technical assistance. This research was supported in part by grant GM 13554 from the U.S. Public Health Service.Attached Files
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Additional details
- PMCID
- PMC224778
- Eprint ID
- 8592
- Resolver ID
- CaltechAUTHORS:KOMpnas68
- U.S. Public Health Service (USPHS)
- GM 13554
- Created
-
2007-08-21Created from EPrint's datestamp field
- Updated
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2019-10-02Created from EPrint's last_modified field