Thermodynamic Aspects of Flagellar Activity
- Creators
- Holwill, M. E.
- Sleigh, M. A.
Abstract
1. The frequencies of the beat of cilia and flagella from various organisms have been determined at temperatures in the range 5-35°C. 2. Values of the activation enthalpy (ΔH{ddagger}, kcal./mole) and activation entropy (ΔS{ddagger}, e.u.) derived from the thermal dependence of frequency show a linear correlation of the form, ΔS{ddagger} = 3.25 ΔH{ddagger}-50.75. 3. The corresponding isokinetic activation free energy is 15.6 kcal./mole. 4. The results support a hypothesis that the breakdown of an ATP-ATPase complex could be the common rate-limiting reaction for flagellar activity. 5. Values of ΔH{ddagger} and ΔS{ddagger} for the decay of length or tension in striated muscles also fall on the same regression line but some smooth muscles show deviations.
Additional Information
© The Company of Biologists Ltd 1967. Submitted on February 24, 1967. This work was supported in part by U.S. Public Health Service grant no. GM14631.Attached Files
Published - HOLjeb67.pdf
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Additional details
- Eprint ID
- 12593
- Resolver ID
- CaltechAUTHORS:HOLjeb67
- GM14631
- Public Health Service
- Created
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2008-12-15Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field