Published March 27, 2000
| Published
Journal Article
Open
An optical coherence microscope for 3-dimensional imaging in developmental biology
Chicago
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Abstract
An optical coherence microscope (OCM) has been designed and constructed to acquire 3-dimensional images of highly scattering biological tissue. Volume-rendering software is used to enhance 3-D visualization of the data sets. Lateral resolution of the OCM is 5 mm (FWHM), and the depth resolution is 10 mm (FWHM) in tissue. The design trade-offs for a 3-D OCM are discussed, and the fundamental photon noise limitation is measured and compared with theory. A rotating 3-D image of a frog embryo is presented to illustrate the capabilities of the instrument.
Additional Information
©2000 Optical Society of America. Received February 02, 2000; Revised March 20, 2000. Support for this work has been provided by a Special Opportunity Award from the Whitaker Foundation to Harvey Mudd College and by a National Science Foundation Grant DBI-9612240.Attached Files
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Additional details
- Eprint ID
- 278
- Resolver ID
- CaltechAUTHORS:HOEoe02
- Whitaker Foundation
- NSF
- DBI-9612240
- Created
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2005-05-16Created from EPrint's datestamp field
- Updated
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2019-10-02Created from EPrint's last_modified field