The Gene Ontology project in 2008

Creators: Gene, Ontology Consortium

Abstract

The Gene Ontology (GO) project (http://www.geneontology.org/) provides a set of structured, controlled vocabularies for community use in annotating genes, gene products and sequences (also see http://www.sequenceontology.org/). The ontologies have been extended and refined for several biological areas, and improvements to the structure of the ontologies have been implemented. To improve the quantity and quality of gene product annotations available from its public repository, the GO Consortium has launched a focused effort to provide comprehensive and detailed annotation of orthologous genes across a number of 'reference' genomes, including human and several key model organisms. Software developments include two releases of the ontology-editing tool OBO-Edit, and improvements to the AmiGO browser interface.

Additional Information

© 2007 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Received September 14, 2007. Accepted October 1, 2007. Nucleic Acids Research Advance Access originally published online on November 4, 2007. The Gene Ontology Consortium is supported by National Human Genome Research Institute (NHGRI) grant HG02273. GO Consortium member databases receive funding from several National Institutes of Health institutes (NHGRI, National Institute of Child Health and Human Development, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences) and by the National Science Foundation, the United States Department of Agriculture Cooperative State Research and Education Service and the UK Medical Research Council. The GO Consortium also thanks the community researchers who have participated in content-related meetings or provided valuable feedback on ontology content and annotations. Funding to pay the Open Access publication charges for this article was provided by NHGRI. Conflict of interest statement. None declared. Supplementary Data are available at NAR Online. [The current members of the GO Consortium are:] Midori A. Harris, Jennifer I. Deegan (née Clark), Amelia Ireland, Jane Lomax (GO-EBI, Hinxton, UK); Michael Ashburner, Susan Tweedie (FlyBase, Department of Genetics, University of Cambridge, Cambridge, UK); Seth Carbon, Suzanna Lewis, Chris Mungall, John Day-Richter (BBOP, LBNL, Berkeley, CA, USA), Karen Eilbeck (Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT, USA), Judith A. Blake, Carol Bult, Alexander D. Diehl, Mary Dolan, Harold Drabkin, Janan T. Eppig, David P. Hill, Li Ni, Martin Ringwald (MGI, The Jackson Laboratory, Bar Harbor, ME, USA); Rama Balakrishnan, Gail Binkley, J. Michael Cherry, Karen R. Christie, Maria C. Costanzo, Qing Dong, Stacia R. Engel, Dianna G. Fisk, Jodi E. Hirschman, Benjamin C. Hitz, Eurie L. Hong, Cynthia J. Krieger, Stuart R. Miyasato, Robert S. Nash, Julie Park, Marek S. Skrzypek, Shuai Weng, Edith D. Wong, Kathy K. Zhu (SGD, Department of Genetics, Stanford University, Stanford, CA, USA); David Botstein, Kara Dolinski, Michael S. Livstone, Rose Oughtred (Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA); Tanya Berardini, Donghui Li, Seung Y. Rhee (TAIR, Carnegie Institution, Department of Plant Biology, Stanford, CA, USA); Rolf Apweiler, Daniel Barrell, Evelyn Camon, Emily Dimmer, Rachael Huntley, Nicola Mulder (GOA Database, UniProt, EBI, Hinxton, UK); Varsha K. Khodiyar, Ruth C. Lovering, Sue Povey (UCL, London, UK); Rex Chisholm, Petra Fey, Pascale Gaudet, Warren Kibbe (dictyBase, Northwestern University, Chicago, IL, USA); Ranjana Kishore, Erich M. Schwarz, Paul Sternberg, Kimberly Van Auken (WormBase, California Institute of Technology, Pasadena, CA, USA); Michelle Gwinn Giglio, Linda Hannick, Jennifer Wortman (The J. Craig Venter Institute, Rockville, MD, USA); Martin Aslett, Matthew Berriman, Valerie Wood (Wellcome Trust Sanger Institute, Hinxton, UK); Howard Jacob, Stan Laulederkind, Victoria Petri, Mary Shimoyama, Jennifer Smith, Simon Twigger (RGD, Medical College of Wisconsin, Milwaukee, WI, USA); Pankaj Jaiswal (Gramene, Department of Plant Breeding, Cornell University, Ithaca, NY, USA); Trent Seigfried (MaizeGDB, UDSA-ARS, Ames, IA, USA); Doug Howe, Monte Westerfield (ZFIN, University of Oregon, Eugene, OR, USA); Candace Collmer (PAMGO, Wells College, Aurora, NY, USA); Trudy Torto-Alalibo (PAMGO, Virginia Bioinformatics Institute, VA, USA); Erika Feltrin, Giorgio Valle (CRIBI, University of Padua, Italy); Susan Bromberg, Shane Burgess, Fiona McCarthy (AgBase, Mississippi State University; MS, USA).

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Resource type: Journal Article
Publisher: Nucleic Acids Research
Published in: Nucleic Acids Research, 36(Supple), D440-D444, ISSN: 0305-1048.

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© 2007 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.