Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published November 1960 | public
Journal Article Open

The biogenesis of the mold tropolones

Abstract

The discovery of the mold metabolites puberulonic acid (I) and puberulic acid (II)(1) and stipitatic acid (III)(2) presented a difficult structural problem to organic chemistry until, in 1945, Dewar(3) made the ingenious proposal of the existence of tropolone (IV) as a new aromatic system. Dewar(3) correctly assigned the structure III to stipitatic acid. The work of Todd and his collaborators(4) led to I for puberulic acid. Aulin-Erdtman(5,6) and Todd et al.(7) showed puberulonic acid to be II. Recently, a fourth mold tropolone, stipitatonic acid, has been characterized(8-10) as V.

Additional Information

© 1960 by the National Academy of Sciences. Communicated by Carl Niemann, September 19, 1960. Presented at the 137th meeting of the American Chemical Society, Cleveland, Ohio, 1960; cf. Abstracts of papers 39-0. A preliminary communication of some of these results has appeared in Biochem. Biophys. Res. Comm., 2, 107 (1960). [J.H.R. was] [a]ided by a grant from the Brown Hazen Fund of the Research Corporation. Gates and Crellin Laboratories of Chemistry, Contribution No. 2630.

Files

FERpnas60.pdf
Files (885.2 kB)
Name Size Download all
md5:41063d93e064f411c797e9c966777937
885.2 kB Preview Download

Additional details

Created:
August 21, 2023
Modified:
October 16, 2023