Published August 1964
| Published
Journal Article
Open
On the RNA synthesized during the lampbrush phase of amphibian oogenesis
- Creators
- Davidson, Eric H.
- Allfrey, V. G.
- Mirsky, A. E.
Abstract
Lampbrush chromosomes have been observed in the growing oocytes of animals ranging from mollusks to mammals. They are present throughout the diplotene of the first meiotic division. These elongate, paired structures bear many thousands of loops projecting laterally from the main chromosomal axis, and they are characteristically accompanied in the nuclear sap by several thousand small nucleoli. It was long ago suggested that the organization of the egg and the early processes of embryogenesis were the result of nuclear activity occurring during ovarian oogenesis,(1) and we now know the lampbrush chromosomes of amphibian oocytes are in a state of intense genetic activity.
Additional Information
© 1964 by the National Academy of Sciences. Communicated June 8, 1964. We are greatly indebted to Mrs. Judith Ann de Graaff for her expert and conscientious technical assistance. This research was supported by a grant (GM 04919-08) from the USPHS.Attached Files
Published - DAVpnas64.pdf
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Additional details
- PMCID
- PMC300305
- Eprint ID
- 7561
- Resolver ID
- CaltechAUTHORS:DAVpnas64
- GM 04919-08
- U.S. Public Health Service (USPHS)
- Created
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2007-03-05Created from EPrint's datestamp field
- Updated
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2023-06-01Created from EPrint's last_modified field