Amino acid adsorption and protein synthesis in Escherichia coli

Abstract

Two quite distinct theories of protein synthesis are currently popular. One holds that amino acids are linked into small peptides which then serve as building blocks for the proteins. The other postulates that amino acids are individually adsorbed on a large template molecule and are then linked together into the polypeptide chains. This paper reports the results of studies of amino acid incorporation by growing Escherichia coli. The results furnish experimental evidence in favor of the template theory.

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