A proposal for the structure of the Drosophila genome
- Creators
- Bonner, James
- Wu, Jung-Rung
Abstract
We propose a structure for the genome of Drosophila melanogaster in which each chromatid of each chromomere (band) consists on the average of about 30-35 different sequences of single-copy (unique) DNA, each on the average about 750 base pairs in length. These are separated from one another by stretches of the middle repetitive (reiterated) DNA, which in D. melanogaster makes up about 15% of the genome. These stretches are about 100-150 base pairs in length and are all of the same sequence or family in each individual chromomere and of a different family (sequence) in each different chromomere. Our proposed structure of the Drosophila genome is in accord with all of the known facts concerning the physical chemistry and molecular biology of Drosophila DNA.
Additional Information
© 1973 by the National Academy of Sciences. Contributed by James Bonner, December 11, 1972. We thank Profs. Eric Davidson, Norman Davidson, and Edward Lewis for their suggestions, advice and counsel, and Prof. Norman Davidson for his tutorials in statistical calculations. This work was supported in part by U.S. Public Health Service Research Grant GM-13762 and in part by a postdoctoral fellowship of the U.S. Public Health Service (J.-R.W.).Attached Files
Published - BONpnas73.pdf
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Additional details
- Eprint ID
- 11910
- Resolver ID
- CaltechAUTHORS:BONpnas73
- GM-13762
- Public Health Service
- Created
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2008-10-16Created from EPrint's datestamp field
- Updated
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2019-10-03Created from EPrint's last_modified field