Published June 15, 1965
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Journal Article
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Recognition of Ribosomal RNA Sites in DNA, I. Analysis of the E. coli System
Chicago
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Abstract
The evidence recently presented of specific hybridization between bacterial ribosomal RNA and homologous DNA1-3 has indicated the possibility of a biochemical approach to the problem of the identification of ribosomal RNA sites in DNA. A difficulty in this approach is that while the specific role of the RNA in the hybridization is open to experimental test, the critical evidence of the unique involvement of presumptive DNA sites is not easily attainable.
Additional Information
Copyright © 1965 by National Academy of Sciences Communicated by Renato Dulbecco, March 22, 1965. We wish to thank Drs. J. Bonner and R. C. Huang for their gift of T4 DNA and pea embryo DNA, and Dr. A. G. DeBusk and E. Brandt for the Neurospora DNA. The capable assistance of Sandra Kiddy is gratefully acknowledged. These investigations were supported by a research grant from the National Institutes of Health (GM-11726).Files
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