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Published July 5, 2023 | Published + Supplemental Material
Journal Article Open

Physically defined long-term and short-term synapses for the development of reconfigurable analog-type operators capable of performing health care tasks

Abstract

Extracting valuable information from the overflowing data is a critical yet challenging task. Dealing with high volumes of biometric data, which are often unstructured, nonstatic, and ambiguous, requires extensive computer resources and data specialists. Emerging neuromorphic computing technologies that mimic the data processing properties of biological neural networks offer a promising solution for handling overflowing data. Here, the development of an electrolyte-gated organic transistor featuring a selective transition from short-term to long-term plasticity of the biological synapse is presented. The memory behaviors of the synaptic device were precisely modulated by restricting ion penetration through an organic channel via photochemical reactions of the cross-linking molecules. Furthermore, the applicability of the memory-controlled synaptic device was verified by constructing a reconfigurable synaptic logic gate for implementing a medical algorithm without further weight-update process. Last, the presented neuromorphic device demonstrated feasibility to handle biometric information with various update periods and perform health care tasks.

Additional Information

© 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). This research was supported by the National Research Foundation (NRF) of Korea grant funded by the Korea government (MSIT) (RS-2023-00234581) and BrainLink program funded by the Ministry of Science and ICT through the NRF of Korea (RS-2023-00237308). This project was partially supported by Sloan Research Fellowship and Heritage Medical Research Institute. Author contributions: Y.C. conducted the fabrication, analysis, and measurement of the synaptic devices and analog-type operator. D.H.H., S.K., Y.J.C., and D.G.R. gave general advice on measuring and analysis of synaptic properties. I.C.K. assisted preparing and processing of 2Bx photocrosslinker. J.M. and H.H. assisted in the study design, device test, and writing the manuscript. W.G. guided the overall direction for biomedical applications of neuromorphic devices. J.H.C. initiated the research and designed the overall experiments. All authors discussed the results and contributed to the paper. The authors declare that they have no competing interests. Data and materials availability: All data needed to evaluate the conclusions in the paper are present in the paper and/or the Supplementary Materials.

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Published - sciadv.adg5946.pdf

Supplemental Material - sciadv.adg5946_sm.pdf

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Additional details

Created:
August 22, 2023
Modified:
October 20, 2023