An autonomous wearable biosensor powered by a perovskite solar cell
Abstract
Wearable sweat sensors can potentially be used to continuously and non-invasively monitor physicochemical biomarkers that contain information related to disease diagnostics and fitness tracking. However, the development of such autonomous sensors faces a number of challenges including achieving steady sweat extraction for continuous and prolonged monitoring and addressing the high power demands of multifunctional and complex analysis. Here we report an autonomous wearable biosensor that is powered by a perovskite solar cell and can provide continuous and non-invasive metabolic monitoring. The device uses a flexible quasi-two-dimensional perovskite solar cell module that provides ample power under outdoor and indoor illumination conditions (power conversion efficiency exceeding 31% under indoor light illumination). We show that the wearable device can continuously collect multimodal physicochemical data—glucose, pH, sodium ion, sweat rate and skin temperature—across indoor and outdoor physical activities for over 12 h.
Additional Information
© 2023 Springer Nature Limited. This project was supported by the National Institutes of Health grants R01HL155815 and R21DK13266, Office of Naval Research grants N00014-21-1-2483 and N00014-21-1-2845, the Translational Research Institute for Space Health through NASA NNX16AO69A, National Science Foundation grant 2145802 (to W.G.) and the European Research Council Starting Grant 'GEL-SYS' under grant agreement no. 757931 (to M.K.). S.D. would like to acknowledge the Marshall Plan Foundation that provided financial support for the three months of research visit to California Institute of Technology that initiated this work. Data availability: All the raw and analysed datasets generated during the study are available from the corresponding authors on request. Source data are provided with this paper. These authors contributed equally: Jihong Min, Stepan Demchyshyn. Contributions: W.G., J.M., M.K. and S.D. initiated the concept and designed the studies. J.M. and S.D. led the experiments and collected the overall data. J.R.S., Y.S., B.H., C.X., Y.Y. and S.S. contributed to the wearable device characterization, validation and sample analysis. B.H., C.P., L.L., M.S. and S.S. contributed to the solar module development, fabrication and characterization. S.D., B.H., J.F.S. and C.S. contributed to the experimental design and characterization of Pb leakage test for the solar cell module. E.S.S. contributed to the cell viability and metabolic activity characterization. J.M., S.D., W.G. and M.K. co-wrote the paper. All authors contributed to the data analysis and provided feedback on the manuscript. The authors declare no competing interests.Attached Files
Supplemental Material - 41928_2023_996_MOESM1_ESM.pdf
Supplemental Material - 41928_2023_996_MOESM3_ESM.mp4
Supplemental Material - 41928_2023_996_MOESM4_ESM.mp4
Supplemental Material - 41928_2023_996_MOESM5_ESM.xlsx
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Additional details
- Eprint ID
- 122436
- Resolver ID
- CaltechAUTHORS:20230725-49211000.21
- URL
- https://rdcu.be/drFZQ
- PMCID
- PMC10923186
- DOI
- 10.1038/s41928-023-00996-y
- NIH
- R01HL155815
- NIH
- R21DK13266
- Office of Naval Research (ONR)
- N00014-21-1-2483
- Office of Naval Research (ONR)
- N00014-21-1-2845
- NASA
- NNX16AO69A
- NSF
- ECCS-2145802
- European Research Council (ERC)
- 757931
- Marshall Plan Foundation
- Created
-
2023-08-15Created from EPrint's datestamp field
- Updated
-
2023-08-15Created from EPrint's last_modified field