Published January 19, 2023
| Submitted
Discussion Paper
Open
The telegraph process is not a subordinator
- Creators
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Gorin, Gennady
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Pachter, Lior
Chicago
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Abstract
Investigations of transcriptional models by Amrhein et al. outline a strategy for connecting steady-state distributions to process dynamics. We clarify its limitations: the strategy holds for a very narrow class of processes, which excludes an example given by the authors.
Additional Information
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license. G.G. and L.P. were partially funded by NIH U19MH114830. The Huang et al. Poisson-Beta solution was implemented in Python by Dr. John J. Vastola, who contributed valuable insights in our broader investigation of continuous and discrete master equations. CODE AVAILABILITY. The Python notebook used to generate Figure 1 is available at https://github.com/pachterlab/GP_2023. The authors have declared no competing interest.Attached Files
Submitted - 2023.01.17.524309v1.full.pdf
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2023.01.17.524309v1.full.pdf
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Additional details
- Eprint ID
- 120150
- Resolver ID
- CaltechAUTHORS:20230316-182495000.36
- NIH
- U19MH114830
- Created
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2023-03-20Created from EPrint's datestamp field
- Updated
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2023-07-05Created from EPrint's last_modified field
- Caltech groups
- Division of Biology and Biological Engineering (BBE)