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Published April 26, 2023 | In Press
Journal Article Open

Spatial tropism profiling of AAV vectors by ultrasensitive sequential FISH in tissue

Abstract

Ultrasensitive sequential fluorescence in situ hybridization (USeqFISH) enables multiplexed detection of the expression of endogenous and exogenous genes delivered by adeno-associated virus (AAV) vectors in intact tissue. USeqFISH provides a spatial map of AAV tropism with high throughput and resolution.

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© 2023 Nature Publishing Group.

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August 22, 2023
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December 22, 2023