Published January 11, 2023
| v2
Journal Article
Open
Synthesis of a Fe₃-Carbyne Motif by Oxidation of an Alkyl Ligated Iron-Sulfur (WFe₃S₃) Cluster
Abstract
The presence of a carbide ligand in the active site of nitrogenases remains an unusual example of organometallic chemistry employed by a protein. Carbide incorporation into the MFe₇S₉ C cluster involves complex biosynthesis, but analogous synthetic methodologies are limited. Herein, we present a new synthetic strategy for incorporating carbon based bridging ligands into iron–sulfur clusters. Starting from a halide precursor, a WFe₃S₃ cluster displaying three terminal alkyl ligands and an open Fe₃ face was prepared. Oxidation results in loss of alkane and formation of a μ3-carbyne. Characterization of these clusters and mechanistic studies are presented.
Additional Information
We are grateful to the National Institutes of Health (R01-GM102687B to T.A.) and the National Science Foundation (Graduate Research Fellowships Program to A.G.S.) for funding. We thank the Beckman Institute and the Dow Next Generation Grant for instrumentation support. Michael Takase is thanked for assistance with crystallography. We are grateful to Paul Oyala for assistance with EPR experiments.Files
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Additional details
- Eprint ID
- 118947
- DOI
- 10.1021/jacs.2c04826
- Resolver ID
- CaltechAUTHORS:20230125-515005200.29
- PMCID
- PMC10575540
- R01-GM102687B
- NIH
- NSF Graduate Research Fellowship
- Caltech Beckman Institute
- Dow Next Generation Educator Fund
- Created
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2023-02-24Created from EPrint's datestamp field
- Updated
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2023-02-24Created from EPrint's last_modified field