Brain-Computer Interfaces for Treatment of Focal Dystonia

Creators: Simonyan, Kristina; Ehrlich, Stefan K.; Andersen, Richard; Brumberg, Jonathan; Guenther, Frank; Hallett, Mark; Howard, Matthew A.; Millán, José del R.; Reilly, Richard B.; Schultz, Tanja; Valeriani, Davide

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Abstract

Task-specificity in isolated focal dystonias is a powerful feature that may successfully be targeted with therapeutic brain–computer interfaces. While performing a symptomatic task, the patient actively modulates momentary brain activity (disorder signature) to match activity during an asymptomatic task (target signature), which is expected to translate into symptom reduction.

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© 2022 International Parkinson and Movement Disorder Society. Version of Record online: 10 August 2022. Manuscript accepted: 19 July 2022. Manuscript revised: 20 June 2022. Manuscript received: 28 March 2022 . Data Availability Statement. Data sharing not applicable to this article as no datasets were generated or analysed during the current study. Research Funding. National Institute on Deafness and Other Communication Disorders. Grant Number: R01DC019353. Radcliffe Institute for Advanced Study at the Harvard University. Relevant conflicts of interest/financial disclosures: Nothing to report.

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Brain-Computer Interfaces for Treatment of Focal Dystonia

Abstract

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