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Published July 14, 2022 | Published
Journal Article Open

Formation of Stable Cruciform Assembly of Gold Nanoparticles from Cannabis indica Leaves

Abstract

Gold nanoparticles have been increasingly used in several electronic, material fabrication, and biomedical applications. Several methods have been reported to prepare gold nanoparticles of various shapes and sizes with different photophysical properties. Although useful to prepare gold nanoparticles, most of the methods are not stable enough, which leads to the degradation of the nanoparticles, if they are stored at room temperatures (up to 30 °C) for a few days. In this paper, we report a novel and environmentally friendly method to synthesize self-assembled gold nanoparticles in cruciform shapes by using leaf extract of Cannabis indica as a reducing agent without the aid of any polymers or additional chemicals. The nanoparticles are found to be stable for more than a month (45 days) when stored at room temperature (up to 30 °C). They were able to form stable conjugates with bovine α-lactalbumin protein that may possess anti-cancerous properties.

Additional Information

© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Received: 9 June 2022 / Revised: 4 July 2022 / Accepted: 7 July 2022 / Published: 13 July 2022. We thank Sunil Kumar Sarangi, Deependra K. Ban, Kunal Pal, Sirsendu Sekhar Ray at the National Institute of Technology, Rourkela for useful discussions. This research received funding from the Department of Biotechnology, Government of India, and the National Institute of Technology, Rourkela, India. Data Availability Statement. All data are present in the manuscript. Additional data can be provided upon reasonable request from the corresponding authors. The authors declare no conflict of interest. Institutional Review Board Statement. Not applicable. Informed Consent Statement. Not applicable.

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Created:
August 22, 2023
Modified:
October 24, 2023