Published May 3, 2019
| Supplemental Material
Journal Article
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Direct Electrochemical Carboxylation of Benzylic C–N Bonds with Carbon Dioxide
Abstract
We report a direct and efficient electrochemical carboxylation of benzylic C–N bonds with CO₂ at room temperature. The reaction has been successfully applied to both primary and secondary benzylic C–N bonds with the compatibility of a variety of functional groups. This procedure does not require stoichiometric metals, external reducing agents, or sacrificial anodes, making column chromatography unnecessary for product purification. Differential electrochemical mass spectrometry (DEMS) was used to elucidate key intermediates of the electrocarboxylation reaction.
Additional Information
© 2019 American Chemical Society. Received2 4 February 2019. Revised 6 April 2019. Published online 11 April 2019. Published in issue 3 May 2019. We gratefully acknowledge financial support from the MIT Energy Initiative Low Carbon Energy Center on Carbon Capture, Utilization, and Storage. We thank IKA for the donation of ElectraSyn 2.0. The authors declare no competing financial interest.Attached Files
Supplemental Material - cs9b00818_si_001.pdf
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cs9b00818_si_001.pdf
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Additional details
- Alternative title
- Direct Electrochemical Carboxylation of Benzylic C-N Bonds with Carbon Dioxide
- Eprint ID
- 114619
- DOI
- 10.1021/acscatal.9b00818
- Resolver ID
- CaltechAUTHORS:20220505-565287000
- Massachusetts Institute of Technology (MIT)
- Created
-
2022-05-06Created from EPrint's datestamp field
- Updated
-
2022-05-06Created from EPrint's last_modified field