Fast quantitative phase imaging based on Kramers-Kronig relations in space domain
Abstract
A fast quantitative phase imaging technology based on space-domain Kramers-Kronig relations is proposed. By incorporating Kramers-Kronig relations, we acquire distributions on phase via measurements of intensity over the captured spectrum. Only using four low-resolution images, we built a microscope prototype with a half-pitch resolution of 625 nm (final effective imaging performance of 0.5 NA) and a field of view of 3.8 mm2 at a wavelength of 625 nm via a 10×/0.25 NA objective. Correspondingly, the data recording time is 0.16 s, and the space-bandwidth-time product is 243.3 megapixels per second. It is worth noting that the proposed scheme requires neither mechanical scanning nor extra illumination like interferometry. Meanwhile, the reconstruction is non-iterative and object-independent. Our method provides a high-efficiency phase retrieval framework and is promising in biomedicine and dynamic observation.
Additional Information
© 2021 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement. Received 28 Sep 2021; revised 14 Nov 2021; accepted 17 Nov 2021; published 24 Nov 2021. Funding: National Natural Science Foundation of China (11874132, 61975044, 12074094); Interdisciplinary Research Foundation of HIT (IR2021237). The authors declare no conflicts of interest. Data availability: Data underlying the results presented in this paper are not publicly available at this time but may be obtained from the authors upon reasonable request.Attached Files
Published - oe-29-25-41067.pdf
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Additional details
- Eprint ID
- 112941
- Resolver ID
- CaltechAUTHORS:20220118-200883600
- 11874132
- National Natural Science Foundation of China
- 61975044
- National Natural Science Foundation of China
- 12074094
- National Natural Science Foundation of China
- IR2021237
- Interdisciplinary Research Foundation
- Harbin Institute of Technology
- Created
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2022-01-18Created from EPrint's datestamp field
- Updated
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2022-01-18Created from EPrint's last_modified field