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Published December 2, 2021 | public
Journal Article

Ir(III) and Ru(II) Complexes in Photoredox Catalysis and Photodynamic Therapy: A New Paradigm towards Anticancer Applications

Abstract

Individually, photoredox catalysis (PC) and photodynamic therapy (PDT) are well-established concepts that have experienced a remarkable resurgence in recent years, leading to significant progress in organic synthesis for PC and clinical approval of anticancer drugs for PDT. But, very recently, new photoredox catalyst systems based on Ir(III) and Ru(II) complexes have garnered significant interest because they can simultaneously be used as PDT agents apart from their demonstrated PC activity. This highlight discusses the unique PC behavior of emerging Ir(III)- and Ru(II)-based systems while also examining their potential PDT activity in cancer treatment.

Additional Information

© 2021 Wiley-VCH GmbH. Issue Online: 02 December 2021; Version of Record online: 06 October 2021; Accepted manuscript online: 24 September 2021; Manuscript revised: 23 September 2021; Manuscript received: 03 September 2021. P.K.S. acknowledges USIEF for supporting the Fulbright-Nehru Postdoctoral Fellowship. The authors declare no conflict of interest.

Additional details

Created:
August 22, 2023
Modified:
October 23, 2023