Published March 1, 2022
| Submitted + Supplemental Material
Journal Article
Open
Optical phased array neural probes for beam-steering in brain tissue
Abstract
Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue is simulated and characterized. The probes are used for optogenetic stimulation and calcium imaging.
Additional Information
© 2022 Optica Publishing Group. Received 26 August 2021; revised 28 November 2021; accepted 9 December 2021; posted 13 December 2021; published 18 February 2022. Funding: National Institutes of Health (NS090596, NS099726); Caltech Kavli Nanoscience Institute; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada. The authors declare no conflicts of interest. Data availability: Data underlying the results presented in this Letter are not publicly available at this time but may be obtained from the authors upon reasonable request.Attached Files
Submitted - 2108.04933.pdf
Supplemental Material - 5575494.pdf
Supplemental Material - Visualization1.mp4
Supplemental Material - Visualization2.mp4
Supplemental Material - Visualization3.mp4
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2108.04933.pdf
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Additional details
- Eprint ID
- 110665
- DOI
- 10.1364/OL.441609
- Resolver ID
- CaltechAUTHORS:20210831-204006744
- NS090596
- NIH
- NS099726
- NIH
- Kavli Nanoscience Institute
- Canadian Institutes of Health Research (CIHR)
- Natural Sciences and Engineering Research Council of Canada (NSERC)
- Created
-
2021-09-01Created from EPrint's datestamp field
- Updated
-
2022-04-05Created from EPrint's last_modified field
- Caltech groups
- Kavli Nanoscience Institute, Division of Biology and Biological Engineering