Published May 14, 2021
| Accepted Version
Journal Article
Open
Investigate the origins of COVID-19
- Creators
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Bloom, Jesse D.
- Chan, Yujia Alina
- Baric, Ralph S.
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Bjorkman, Pamela J.
- Cobey, Sarah
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Deverman, Benjamin E.
- Fisman, David N.
- Gupta, Ravindra
- Iwasaki, Akiko
- Lipsitch, Marc
- Medzhitov, Ruslan
- Neher, Richard A.
- Nielsen, Rasmus
- Patterson, Nick
- Stearns, Tim
- van Nimwegen, Erik
- Worobey, Michael
- Relman, David A.
Abstract
On 30 December 2019, the Program for Monitoring Emerging Diseases notified the world about a pneumonia of unknown cause in Wuhan, China (1). Since then, scientists have made remarkable progress in understanding the causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), its transmission, pathogenesis, and mitigation by vaccines, therapeutics, and non-pharmaceutical interventions. Yet more investigation is still needed to determine the origin of the pandemic. Theories of accidental release from a lab and zoonotic spillover both remain viable. Knowing how COVID-19 emerged is critical for informing global strategies to mitigate the risk of future outbreaks.
Additional Information
© 2021 American Association for the Advancement of Science. This is an article distributed under the terms of the Science Journals Default License.Attached Files
Accepted Version - nihms-1834584.pdf
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Additional details
- PMCID
- PMC9520851
- Eprint ID
- 109115
- Resolver ID
- CaltechAUTHORS:20210513-115757419
- Created
-
2021-05-13Created from EPrint's datestamp field
- Updated
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2023-07-07Created from EPrint's last_modified field
- Caltech groups
- COVID-19, Division of Biology and Biological Engineering (BBE)