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Published January 26, 2021 | public
Book Section - Chapter

Single Molecule Studies of a Biological Motor F₁-ATPase: Interplay of Experiment, Analytic Theory and Computation

Abstract

In this chapter we discuss the interaction between theory and single molecule experiments on a biological motor, F₁-ATPase. In particular, we consider an interplay between the experiment, analytical theory, and computer simulations. The complementarity of the millisecond and microsecond experiments is noted. For example, the limited experiments on the latter indicate that the ATP binding in one β subunit precedes an ADP release in another β subunit, whereas the millisecond experiments do not time-resolve the two steps.

Additional Information

© Springer Nature Switzerland AG 2021. First Online: 26 January 2021. This work was supported by the Office of the Naval Research, the Army Research Office, and the James W. Glanville Foundation.

Additional details

Created:
August 20, 2023
Modified:
January 15, 2024