Published August 15, 1970 | public
Journal Article

Postsynaptic Action of Cobra Toxin at the Myoneural Junction

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Abstract

Recent investigations of peptide fractions from cobra venoms suggest that the most potent acute toxicity arises from a curare-like block of the action of acetylcholine at the skeletal myoneural junction. I wish to report the effects on myoneural transmission of toxin T₃ from Naja naja siamensis—(Kaouthia) (Thailand cobra) venom, a pure peptide of known amino-acid composition.

Additional Information

© 1970 Nature Publishing Group. Received April 2, 1970. thank Mr D. Eaker for toxin and Mr F. A. Dodge, Mr. A. Mauro, and Mr F. Ratliff for advice. This work was supported by grants from tho National Institutes of Neurological Diseases and Blindness and the National Science Foundation and by a predoctoral fellowship from the National Institutes of Health.

Additional details

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August 19, 2023
Modified:
October 20, 2023