Published August 12, 2020
| Published
Journal Article
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Cannabis Extract Composition Determines Reinforcement in a Vapor Self-Administration Paradigm
- Creators
- Muthusamy, Anand K.
Abstract
The legalization of cannabis and shifting cultural attitudes have driven an increase in cannabis use and the proliferation of vapor delivery devices. The DSM-V recognizes "cannabis use disorder" under the umbrella of substance use disorders, but its neural mechanisms require greater clarity (Peters et al., 2020). Debate in the scientific community and the public sphere alike primarily asks, "is cannabis addictive?" and "are there negative effects from chronic use?" The first issue magnifies the second: if users compulsively seek cannabis or become dependent, then safe regimens become difficult to maintain.
Additional Information
© 2020 the authors. Beginning six months after publication the Work will be made freely available to the public on SfN's website to copy, distribute, or display under a Creative Commons Attribution 4.0 International (CC BY 4.0) license (https://creativecommons.org/licenses/by/4.0/) Received Apr. 7, 2020; revised June 21, 2020; accepted June 26, 2020. I thank my adviser Dr. Henry A. Lester for guidance in the neuroscience of addiction; and Vinicius S. Ferreira for helpful comments on the manuscript. This work was supported by the National Institute on Drug Abuse grant DA049140.Attached Files
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Additional details
- PMCID
- PMC7424876
- Eprint ID
- 104939
- Resolver ID
- CaltechAUTHORS:20200812-141349529
- DA049140
- NIH
- Created
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2020-08-12Created from EPrint's datestamp field
- Updated
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2023-06-01Created from EPrint's last_modified field