Published September 2020
| public
Journal Article
New players on the piRNA field
- Creators
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Ninova, Maria
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Fejes Tóth, Katalin
Abstract
The nuclear piRNA pathway safeguards genome integrity in the germline by silencing transposable elements. Three recent studies have identified new players in the mammalian pathway. Two of these, TEX15 and SPOCD1, might provide a link between piRNA-guided complexes that recognize genomic targets and the molecular machinery that induces DNA methylation and transcriptional repression during mouse spermatogenesis.
Additional Information
© 2020 Nature Publishing Group. Published: 12 August 2020; Issue Date: September 2020. The authors declare no competing interests.Additional details
- Eprint ID
- 104931
- DOI
- 10.1038/s41594-020-0484-7
- Resolver ID
- CaltechAUTHORS:20200812-120210398
- Created
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2020-08-12Created from EPrint's datestamp field
- Updated
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2021-11-16Created from EPrint's last_modified field
- Caltech groups
- Division of Biology and Biological Engineering