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Published January 2006 | public
Journal Article

Dendritic architecture of the von Economo neurons

Abstract

The von Economo neurons are one of the few known specializations to hominoid cortical microcircuitry. Here, using a Golgi preparation of a human postmortem brain, we describe the dendritic architecture of this unique population of neurons. We have found that, in contrast to layer 5 pyramidal neurons, the von Economo neurons have sparse dendritic trees and symmetric apical and basal components. This result provides the first detailed anatomical description of a neuron type unique to great apes and humans.

Additional Information

© 2006 IBRO. Published by Elsevier Ltd. Accepted 26 April 2006, Available online 22 June 2006. We thank the James S. McDonnell, Gordon and Betty Moore, David and Lucile Packard, Howard Hughes Institute, and Swartz Foundations for their generous support of this work, and Jason Kaufman for his assistance in the preparation of the photomicrographs. We also thank Patrick Codd for help with the Neurolucida tracing, and Dr. Bill Yong for providing us with the specimens for pilot study. The brain used in this study of normal subjects was provided by the NICHD Brain and Tissue Bank for Developmental Disorders at the University of Maryland under contract N01-HD-4-3368.

Additional details

Created:
August 22, 2023
Modified:
October 20, 2023