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Published July 2020 | public
Journal Article

Pachytene piRNAs as beneficial regulators or a defense system gone rogue

Abstract

Pachytene Piwi-interacting RNAs (piRNAs) are abundant small non-coding RNAs expressed in mammalian germ lines. A new study indicates that, among the diverse pool of piRNA sequences, a small number act as highly selective guides that induce cleavage of coding and non-coding transcripts, thus promoting piRNA generation and regulating gene expression.

Additional Information

© 2020 Springer Nature Limited. Published 29 June 2020. The author declares no competing interests.

Additional details

Created:
August 19, 2023
Modified:
December 22, 2023