Published August 7, 2020
| Accepted Version
Journal Article
Open
Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions
Abstract
Nickel-catalyzed reductive cross-coupling reactions have emerged as powerful methods to join two electrophiles. These reactions have proven particularly useful for the coupling of sec-alkyl electrophiles to form stereogenic centers; however, the development of enantioselective variants remains challenging. In this Perspective, we summarize the progress that has been made toward Ni-catalyzed enantioselective reductive cross-coupling reactions.
Additional Information
© 2020 American Chemical Society. Received: April 24, 2020; Revised: June 19, 2020; Published: June 24, 2020. Fellowship support was provided by the National Science Foundation (graduate research fellowship to K.E.P., S.E.D. Grant No. DGE-1144469). S.E.R. is a Heritage Medical Research Institute Investigator. Financial support from the NIH (R35GM118191-01) is gratefully acknowledged. The authors declare no competing financial interest.Attached Files
Accepted Version - nihms-1608630.pdf
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nihms-1608630.pdf
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Additional details
- PMCID
- PMC7470226
- Eprint ID
- 104020
- DOI
- 10.1021/acscatal.0c01842
- Resolver ID
- CaltechAUTHORS:20200624-154304037
- DGE-1144469
- NSF Graduate Research Fellowship
- Heritage Medical Research Institute
- R35GM118191-01
- NIH
- Created
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2020-06-25Created from EPrint's datestamp field
- Updated
-
2022-02-09Created from EPrint's last_modified field
- Caltech groups
- Heritage Medical Research Institute