Published June 1993
| public
Journal Article
Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system
- Creators
- Liou, Hsiou-Chi
-
Baltimore, David
Chicago
Abstract
The interplay between proteins of the NF-ηB/rel and IηB families is a tightly regulated process that ensures appropriate responses to specific environmental and developmental signals. Various mechanisms are utilized in regulating NF-ηB/rel and IxB activities, some unique to this transcription factor system. All of these regulatory strategies converge towards one purpose, namely the controlled nuclear translocation of activated NF-ηB/rel protein complexes. The variety of rel-related and ankyrin repeat containing subunits makes regulation of this system both rich and complicated.
Additional Information
© 1993 Published by Elsevier Ltd. We thank Drs M Scott, W Pear, Z-S Ye and B Sha for critical comments on this manuscript. We also appreciate Drs G Nolan, T Fujita, R Bravo, R DaIla-Favera, I Verma, S Wasserman and S Gerondakis among others for sharing information with us prior to publication.Additional details
- Eprint ID
- 103185
- Resolver ID
- CaltechAUTHORS:20200513-144023678
- Created
-
2020-05-13Created from EPrint's datestamp field
- Updated
-
2021-11-16Created from EPrint's last_modified field