Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published June 1993 | public
Journal Article

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

Abstract

The interplay between proteins of the NF-ηB/rel and IηB families is a tightly regulated process that ensures appropriate responses to specific environmental and developmental signals. Various mechanisms are utilized in regulating NF-ηB/rel and IxB activities, some unique to this transcription factor system. All of these regulatory strategies converge towards one purpose, namely the controlled nuclear translocation of activated NF-ηB/rel protein complexes. The variety of rel-related and ankyrin repeat containing subunits makes regulation of this system both rich and complicated.

Additional Information

© 1993 Published by Elsevier Ltd. We thank Drs M Scott, W Pear, Z-S Ye and B Sha for critical comments on this manuscript. We also appreciate Drs G Nolan, T Fujita, R Bravo, R DaIla-Favera, I Verma, S Wasserman and S Gerondakis among others for sharing information with us prior to publication.

Additional details

Created:
August 20, 2023
Modified:
October 20, 2023