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Published September 2020 | Published + Supplemental Material
Journal Article Open

The chemosensory systems of Vibrio cholerae

Abstract

Vibrio cholerae, the causative agent of the acute diarrheal disease cholera, is able to thrive in diverse habitats such as natural water bodies and inside human hosts. To ensure their survival, these bacteria rely on chemosensory pathways to sense and respond to changing environmental conditions. These pathways constitute a highly sophisticated cellular control system in Bacteria and Archaea. Reflecting the complex life cycle of V. cholerae, this organism has three different chemosensory pathways that together contain over 50 proteins expressed under different environmental conditions. Only one of them is known to control motility, while the function of the other two remains to be discovered. Here, we provide an overview of the chemosensory systems in V. cholerae and the advances toward understanding their structure and function.

Additional Information

© 2020 The Authors. Molecular Microbiology published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Issue Online: 17 September 2020; Version of Record online: 13 May 2020; Accepted manuscript online: 29 April 2020; Manuscript accepted: 16 April 2020; Manuscript revised: 16 April 2020; Manuscript received: 17 December 2019.

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Published - mmi.14520.pdf

Supplemental Material - mmi14520-sup-0001-tables1.pdf

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Created:
August 19, 2023
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October 20, 2023