Tailored nanodiamonds for hyperpolarized ¹³C MRI
Abstract
Nanodiamond is poised to become an attractive material for hyperpolarized ¹³C magnetic resonance imaging if large nuclear polarizations can be achieved without the accompanying rapid spin-relaxation driven by paramagnetic species. Here we report enhanced and long-lived ¹³C polarization in synthetic nanodiamonds tailored by acid-cleaning and air-oxidation protocols. Our results separate the contributions of different paramagnetic species on the polarization behavior, identifying the importance of substitutional nitrogen defect centers in the nanodiamond core. These results are likely of use in the development of nanodiamond-based imaging agents with size distributions of relevance for examining biological processes.
Additional Information
© 2020 Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Received 13 September 2019; accepted 23 March 2020; published 17 April 2020. The authors acknowledge the support of the Australian Research Council Centre of Excellence Scheme (Grant No. EQuS CE110001013) and ARC DP1094439. We also acknowledge use of the EPR tools provided by the NMR Facility within the Mark Wainwright Analytical Centre at the University of New South Wales.Attached Files
Published - PhysRevB.101.155416.pdf
Submitted - 1909.04842.pdf
Supplemental Material - Supplementary.pdf
Files
Additional details
- Eprint ID
- 102613
- Resolver ID
- CaltechAUTHORS:20200417-141254375
- CE110001013
- Australian Research Council
- DP1094439
- Australian Research Council
- Created
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2020-04-17Created from EPrint's datestamp field
- Updated
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2021-11-16Created from EPrint's last_modified field