Welcome to the new version of CaltechAUTHORS. Login is currently restricted to library staff. If you notice any issues, please email coda@library.caltech.edu
Published February 15, 2007 | public
Journal Article

A floating metal microelectrode array for chronic implantation

Abstract

Implantation of multi-electrode arrays is becoming increasingly more prevalent within the neuroscience research community and has become important for clinical applications. Many of these studies have been directed towards the development of sensory and motor prosthesis. Here, we present a multi-electrode system made from biocompatible material that is electrically and mechanically stable, and employs design features allowing flexibility in the geometric layout and length of the individual electrodes within the array. We also employ recent advances in laser machining of thin ceramic substrates, application of ultra-fine line gold conductors to ceramic, fabrication of extremely flexible cables, and fine wire management techniques associated with juxtaposing metal microelectrodes within a few hundred microns of each other in the development of a floating multi-electrode array (FMA). We implanted the FMA in rats and show that the FMA is capable of recording both spikes and local field potentials.

Additional Information

© 2006 Elsevier B.V. Received 3 May 2006, Revised 25 August 2006, Accepted 1 September 2006, Available online 25 October 2006. The authors wish to thank Cevat Ustun, Eunjung Huang, Tessa Yao, Viktor Shcherbatyuk, Nicole Sammons and Kelsie Pejsa. We also thank the Defense Advanced Research Projects Agency (DARPA), The Swartz-Sloan Center for Theoretical Neurobiology, The National Institute of Health (NIH), The McKnight Foundation and the Industrial Outreach funds for the NSF Center for Neuromorphic Systems Engineering ERC at Caltech. The FMA microelectrode systems were developed in cooperation with Micro Probe, Inc. and in part through a SBIR Phase I grant to Micro Probe, Inc., number R43NS051036-01.

Additional details

Created:
August 22, 2023
Modified:
October 19, 2023