Published April 17, 2020
| Accepted Version + Supplemental Material
Journal Article
Open
Enhanced Synthetic Access to Tris-CF₃-Substituted Corroles
Abstract
Separate focus on the oligomerization and oxidative cyclization steps required for the synthesis of 5,10,15-tris(trifluoromethyl)corrole revealed [bis(trifluoroacetoxy)iodo]benzene (PIFA) as a superior alternative oxidant. Under optimized conditions, the pure free-base corrole was obtained with a 6-fold increase in chemical yield and an 11-fold rise in isolated material per synthesis. The corresponding gallium(III) and manganese(III) complexes were isolated by adding the appropriate metal salt prior to corrole purification.
Additional Information
© 2020 American Chemical Society. Received: March 9, 2020; Published: March 31, 2020. This research was supported by the Israel Science Foundation (to ZG) and the United States National Institutes of Health (R01 DK019038 to HBG). Author Contributions: P.Y. and S.K. made equal contributions. The authors declare no competing financial interest.Attached Files
Accepted Version - nihms-1583218.pdf
Supplemental Material - ol0c00879_si_001.pdf
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Additional details
- PMCID
- PMC7187640
- Eprint ID
- 102207
- DOI
- 10.1021/acs.orglett.0c00879
- Resolver ID
- CaltechAUTHORS:20200331-133818896
- Israel Science Foundation
- R01 DK019038
- NIH
- Created
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2020-03-31Created from EPrint's datestamp field
- Updated
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2023-07-20Created from EPrint's last_modified field