Published October 2019
| public
Journal Article
The Pre-pregnancy Rheumatoid Arthritis Gene Expression Signature Correlates with Improvement or Worsening of Disease Activity During Pregnancy: A Pilot Study
Abstract
Pregnancy is known to induce a natural improvement of Rheumatoid Arthritis (RA) symptoms in 50- 75% of patients as gestation progresses. However, the underlying mechanisms are not well understood and no biomarkers have been identified that predict whether a woman will improve or worsen during pregnancy. In this study, we aimed to identify RA- associated pre- pregnancy gene expression signatures to determine if they correlated with the subsequent improvement or worsening of RA during pregnancy.
Additional Information
© 2019 American College of Rheumatology. Issue Online: 29 October 2019; Version of Record online: 29 October 2019. Disclosure: A. Pathi , None; M. Smed , None; L. Pachter , None; E. Purdom , None; M. Wright , None; N. Jewell, None; J. Nelson , None; J. Olsen , None; M. Lund Hetland , Abbvie, 2, AbbVie, 2, Biogen, 2, BMS, 2, CellTrion, 2, 9, MSD, 2, Novartis, 2, Orion, 2, Pfizer, 2, Samsung, 2, UCB, 2; V. Zoffmann , None; D. Jawaheer , None.Additional details
- Eprint ID
- 101173
- DOI
- 10.1002/art.41108
- Resolver ID
- CaltechAUTHORS:20200206-125453251
- Created
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2020-02-06Created from EPrint's datestamp field
- Updated
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2021-11-16Created from EPrint's last_modified field