A Cortical Region Consisting Entirely of Face-Selective Cells
Abstract
Face perception is a skill crucial to primates. In both humans and macaque monkeys, functional magnetic resonance imaging (fMRI) reveals a system of cortical regions that show increased blood flow when the subject views images of faces, compared with images of objects. However, the stimulus selectivity of single neurons within these fMRI-identified regions has not been studied. We used fMRI to identify and target the largest face-selective region in two macaques for single-unit recording. Almost all (97%) of the visually responsive neurons in this region were strongly face selective, indicating that a dedicated cortical area exists to support face processing in the macaque.
Additional Information
© 2006 American Association for the Advancement of Science. Received 9 September 2005; accepted 5 December 2005. We thank B. Moghaddam and T. Poggio for discussions; D. Hubel, C. Gross, and G. Yovel for comments on the manuscript; T. Chuprina, D. Freeman, S. Moeller, N. Nallasamy, N. Schweers, W. Vanduffel, and members of the Massachusetts General Hospital monkey fMRI group for technical assistance; and A. Dale and A. van der Kouwe for allowing us to use their multiecho sequence and undistortion algorithm. This work was supported by NIH (grant nos. EY13135 and EY13025), P41:RR14075, and the Mental Illness and Neuroscience Discovery (MIND) Institute. D.Y.T is supported by a Sofia Kovalevksaya Award from the Alexander von Humboldt Foundation.Attached Files
Accepted Version - nihms86939.pdf
Supplemental Material - Tsao.SOMreduced.pdf
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Additional details
- PMCID
- PMC2678572
- Eprint ID
- 100808
- Resolver ID
- CaltechAUTHORS:20200121-083323880
- EY13135
- NIH
- EY13025
- NIH
- P41:RR14075
- NIH
- Mental Illness and Neuroscience Discovery (MIND) Institute
- Alexander von Humboldt Foundation
- Created
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2020-01-21Created from EPrint's datestamp field
- Updated
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2021-11-16Created from EPrint's last_modified field