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Published January 9, 2020 | public
Journal Article

Deconstructive Functionalization of Ketones via an LMCT-Promoted C–C Cleavage

Abstract

In this issue of Chem, Zuo and coworkers report an exciting new strategy for the deconstructive functionalization of ketones. Through merging Lewis-acid-catalyzed nucleophilic 1,2-addition and ligand-to-metal charge transfer (LMCT)-promoted C–C cleavage, common strained and unstrained ketones are transformed into synthetically valuable scaffolds with high efficiency under mild conditions.

Additional Information

© 2019 Elsevier Inc. Available online 9 January 2020.

Additional details

Created:
August 19, 2023
Modified:
October 18, 2023