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Published January 2019 | public
Book Section - Chapter

Development of Gas Permeable Parylene HT as a Substrate for Cell-Culture-on-a-Chip Applications

Abstract

Here we report on the production of highly gas permeable Parylene HT through a cryogenic deposition process. The unique combination of biological and chemical inertness of Parylene, and gas permeability of this porous variant make it interesting for cell culture and biology-on-a-chip applications. The dependence of porosity, density, and permeability on the deposition temperature allows for tunable control of material properties. Culture of HEK-293 cells on cryogenically deposited Parylene HT demonstrates viability for biological applications.

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© 2019 IEEE.

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Created:
August 19, 2023
Modified:
October 18, 2023