Published June 28, 2006
| public
Book Section - Chapter
Nanoscale Molecular Transport by Synthetic DNA Machines
- Creators
- Shin, Jong-Shik
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Pierce, Niles A.
Abstract
Biological systems have evolved motor proteins programmed to perform intracellular transport powered by ATP hydrolysis [23, 14]. Striding along a microtubule with a hand-over-hand gait and a step size of ≈8 nm [26], kinesin is capable of taking ≈100 steps per second, typically negotiating ≈100 steps before falling off the microtubule [4]. Replicating these performance characteristics with a synthetic mimic presents a daunting challenge to molecular engineers pursuing programmable active transport as a means to assembling or probing nanoscale systems.
Additional Information
© 2006 Springer-Verlag Berlin Heidelberg. This work was supported by DARPA and the Air Force Research Laboratory, the Ralph M. Parsons Foundation, the Charles Lee Powell Foundation, and the Caltech Center for Biological Circuit Design.Additional details
- Eprint ID
- 99277
- Resolver ID
- CaltechAUTHORS:20191015-134801443
- Defense Advanced Research Projects Agency (DARPA)
- Air Force Research Laboratory (AFRL)
- Ralph M. Parsons Foundation
- Charles Lee Powell Foundation
- Caltech Center for Biological Circuit Design
- Created
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2019-10-15Created from EPrint's datestamp field
- Updated
-
2021-11-16Created from EPrint's last_modified field
- Series Name
- Natural Computing Series