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Published June 1985 | public
Journal Article

pH Sensitization of Phospholipid Vesicles via Complexation with Synthetic Poly(carboxylic acid)s

Abstract

Controlled release of vesicle-entrapped substances in response to changes in environmental conditions may provide a basis for new technologies in pharmaceutics, in imaging, in sensing, or in medical diagnostics. We describe in this paper a fundamentally new method of producing pH-sensitive vesicles from pH-insensitive amphiphiles, a method that consists of complexation of the amphiphile with a pH-sensitive polyelectrolyte.

Additional Information

© 1985 New York Academy of Sciences. This research was supported in part by an Alfred P. Sloan Research Fellowship to D.A.T. and in part by a grant from 3M. Part 7 in a series, "Interactions of Synthetic Polymers with Cell Membranes and Model Membrane Systems."

Additional details

Created:
August 19, 2023
Modified:
October 19, 2023