Published December 5, 2019
| Supplemental Material
Journal Article
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Selective Deprotection of the Diphenylmethylsilyl (DPMS) Hydroxyl Protecting Group Under Environmentally Responsible, Aqueous Conditions
Abstract
Two new methods for deprotection of diphenylmethylsilyl (DPMS) ethers are described. Selective unmasking can be achieved with either catalytic amounts of perfluoro‐1‐butanesulfonyl fluoride (a SuFEx reagent) under mild, aqueous micellar conditions, or using stoichiometric amounts of 18‐crown‐6 ether in aqueous ethanol.
Additional Information
© 2019 WILEY‐VCH. Issue Online: 02 December 2019; Version of Record online: 04 October 2019; Accepted manuscript online: 09 September 2019; Manuscript received: 11 July 2019. Funding Information: Novartis (Basel).Attached Files
Supplemental Material - cctc201901232-sup-0001-misc_information.pdf
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cctc201901232-sup-0001-misc_information.pdf
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Additional details
- Eprint ID
- 98527
- Resolver ID
- CaltechAUTHORS:20190909-133648891
- Novartis
- Created
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2019-09-09Created from EPrint's datestamp field
- Updated
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2023-09-28Created from EPrint's last_modified field