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Published April 2006 | Published
Journal Article Open

Progress in Lithotripsy Research

Abstract

Shock wave lithotripsy (SWL) for the non-invasive treatment of kidney stones was introduced in the United States in 1984. SWL virtually eliminated the need for open surgery to remove kidney stones, and it did not take long for physicians and patients to endorse this revolutionary technology. Early reports told of the efficient removal of even the most troublesome stones without apparent complications, and SWL quickly became the "treatment modality of choice." It was not long, however, before concerned physicians began to report the occurrence of adverse effects in SWL, particularly involving vascular trauma and including cases of severe hemorrhage in the kidney and acute renal failure — significant side effects of serious consequence. Researchers quickly recognized the challenge and opportunity to determine the mechanisms of shock wave action in lithotripsy, and in 1988, the Acoustical Society of America held the first in a series of popular sessions devoted to the topic of shock waves in medicine. The goal of the inaugural session was to improve the fundamental understanding of lithotripsy — to bring better devices and treatments to patients. The goal of this paper is to report on progress in this effort.

Additional Information

© 2006 Acoustical Society of America. This work was supported by National Institutes of Health (NIH) (DK43881, DK55674, Fogarty International Research Collaboration Award (FIRCA)), Office of Naval Research International Field Office (ONRIFO), U.S. Civilian Research and Development Foundation (CRDF), and National Space Biomedical Research Institute (NSBRI) SMS00402. The National Institute of Diabetes and Digestive and Kidney Diseases has maintained lithotripsy research as a priority area for over 15 years. We thank the Center for Industrial and Medical Ultrasound and the Consortium for Shock Waves in Medicine, in particular, Prof. Oleg A. Sapozhnikov (Moscow State University), Prof. Robin O. Cleveland (Boston University), Prof. Lawrence A. Crum (University of Washington), students Adam Maxwell (University of Washington), Eric Johnsen (California Institute of Technology) and Parag Chitnis (Boston University) for data and figures presented.

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August 19, 2023
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